Therapeutic Area

aCROss ATMPs

From Gene Therapy to Cell Therapy - ATMP Trials Built for Complexity

Discuss Your Study

Advanced therapy medicinal products - gene therapies, cell therapies and tissue-engineered products - are the most complex and fastest-growing segment of clinical research. ATMP trials demand cold chain logistics, chain-of-custody controls and regulatory frameworks that few CROs are built to handle.

aCROss Medical is building dedicated ATMP trial capabilities across our site network in Georgia, Armenia, Israel and Uzbekistan, with Israel's world-class haematology and oncology centres providing particularly strong CAR-T and gene therapy experience.

Every Subspecialty Has Its Challenges. We Know Them All.

Oncology
CAR-T cell therapies, TCR-engineered T cells and oncolytic viruses.
Rare Genetic Diseases
Gene replacement and gene editing therapies for inherited disorders.
Haematology
Haematopoietic stem cell and gene therapies for blood disorders.
Ophthalmology
Retinal gene therapies and cell-based treatments for vision loss.
Neurology
CNS gene therapies for neurodegenerative conditions.
Cardiovascular & Vascular
Cardiac cell therapies and peripheral vascular regeneration.

What Sets Us Apart in ATMP Trials

ATMP-Trained Teams

Investigators and site staff trained in chain-of-identity, chain-of-custody and ATMP-specific handling procedures.

Specialist Site Network

Academic medical centres with CAR-T, gene therapy and cell therapy experience across Israel, Georgia and Armenia.

Cold Chain & Logistics

Cryogenic storage, apheresis coordination and cell collection logistics built for complex biologics.

Enhanced Pharmacovigilance

Rigorous safety reporting and long-term follow-up (LTFU) management for ATMP-specific risks.

Regulatory Expertise

Strategy aligned with ICH E6(R2), EU ATMP Regulation (EC No 1394/2007) and local authority requirements.

Client Testimonial

aCROss was introduced to us through a mutual connection. At the outset of our trial, we had limited experience working outside the U.S. regulatory environment and needed to familiarize ourselves with the processes and operational landscape in Georgia. From the very beginning of our collaboration, it became clear that this would be more than a typical CRO partnership; it would be a true team effort, supporting us at every stage from regulatory approvals to site qualification, initiation and monitoring visits.

To us, aCROss represents professionalism, dedication, and exceptional availability. We have full confidence in their expertise and judgment in all aspects of our study, and we now look forward to continuing this successful collaboration in Phase 3.

YP
Dr. Yael Porat and the BioGenCell team
BioGenCell

Other Therapeutic Areas

ICU General Surgery Infectious Disease Oncology Respiratory Vascular

Let's Talk About Your ATMP Study

Whether you're developing a CAR-T programme, a gene therapy for a rare disease, or a cell-based regenerative treatment - we'd love to hear about your study.

Discuss Your Study